RCOR1

Across TCGA pan-cancer cohorts, RCOR1 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of RCOR1’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where RCOR1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RCOR1 is over-expressed in tumor, although a few such as LUAD and THCA show the opposite, repressed pattern.

LIHC, HNSC, and UCEC are the cancer types where RCOR1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RCOR1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	All	II,III,IV	+0.738	<.001	9	view →
HNSC	All	All	+0.576	.002	7	view →
UCEC	All	II,III,IV	+0.835	.010	6	view →
LUAD	All	All	−0.338	<.001	5	view →
CHOL	Male	All	+1.753	<.001	4	view →
LUSC	Male	III,IV	+1.260	.013	4	view →
BRCA	All	II,III,IV	+0.434	<.001	4	view →
BLCA	Male	III,IV	+0.798	.019	3	view →
THCA	All	All	−0.258	.004	3	view →
PAAD	All	All	+0.735	.030	2	view →
STAD	All	II,III,IV	+0.571	.023	2	view →
PRAD	All	All	+0.249	.032	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

RCOR1–LIHC

Open the LIHC breakdown →