RCN3

Across TCGA patient cohorts, RCN3 mutation is significantly associated with the RNA expression of many other genes, with 286 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RCN3-associated genes across cancer lineages are RPL18AP17, RN7SL83P, and TDGP1. Each is linked with RCN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RCN3-to-partner and partner-to-RCN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL18AP17 grouped by RCN3-low versus RCN3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RCN3→partner) and Y-score (partner→RCN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPL18AP17 →	+0.098	+3.226	.001	.005	3	2
UCEC	RN7SL83P →	+0.183	+2.523	<.001	.008	3	2
UCEC	TDGP1 →	+0.131	+2.338	.002	.007	3	2
UCEC	VDAC3P1 →	+0.360	+2.595	<.001	.005	3	1
UCEC	FCGBP →	-1.109	-2.689	.007	.006	3	1
UCEC	MIR6133 →	+0.285	+2.523	.005	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 286 associations by consensus.

RPL18AP17 by RCN3 expression — UCEC

Explore this box plot interactively →