RCN2

Across TCGA patient cohorts, RCN2 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RCN2-associated genes across cancer lineages are eEF2, EGFR_pY1068, and eIF4E. Each is linked with RCN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RCN2-to-partner and partner-to-RCN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by RCN2-low versus RCN2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RCN2→partner) and Y-score (partner→RCN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.422	+1.700	.005	.044	3	1
UCEC	EGFR_pY1068 →	-0.288	-2.222	.006	.011	3	1
UCEC	eIF4E →	+0.227	+2.222	.011	.011	3	1
UCEC	A-Raf_pS299 →	-0.180	-3.169	<.001	.019	3	1
UCEC	IGFBP2 →	-0.689	-1.700	.012	.044	3	1
UCEC	INPP4B →	-0.356	-3.459	.009	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

eEF2 by RCN2 expression — UCEC

Explore this box plot interactively →