RCN1

Across TCGA pan-cancer cohorts, RCN1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated RCN1 data layer compared with 5 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher RCN1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RCN1 expression acts as an unfavorable survival marker, although some lineages such as READ and LAML show a favorable association.

MESO, ACC, and KIRP are the cancer types where RCN1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.419	0.665	<.001	114	view →
ACC	DFS	Median	All	0.402	0.756	<.001	106	view →
KIRP	DFS	Quartile	All	0.586	0.863	<.001	84	view →
LIHC	OS	Median	All	0.378	0.663	<.001	64	view →
LUAD	DFS	Median	All	0.264	0.424	<.001	58	view →
LUSC	DFS	Quartile	III,IV	0.212	0.935	.002	36	view →
LGG	OS	Median	All	0.743	0.876	<.001	36	view →
CESC	DFS	Median	All	0.432	0.629	.006	26	view →
PAAD	DFS	Median	II,III,IV	0.340	0.593	.002	22	view →
READ	DFS	Quartile	II,III,IV	0.965	0.611	.004	20	view →
HNSC	OS	Quartile	II,III,IV	0.694	0.783	.021	19	view →
LAML	DFS	Quartile	All	0.769	0.534	.018	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

RCN1–MESO (OS)

Open the MESO breakdown →