RCCD1

Across TCGA pan-cancer cohorts, RCCD1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RCCD1 data layer compared with 25 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RCCD1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RCCD1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and UCEC show a favorable association.

CCRCC, HNSC, and PDAC are the cancer types where RCCD1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	All	0.982	0.723	.004	14	view →
HNSC	DFS	Quartile	All	0.598	0.954	.008	13	view →
PDAC	DFS	Quartile	III,IV	0.245	0.835	.024	9	view →
UCEC	DFS	Median	All	0.926	0.796	.036	2	view →
GBM	DFS	Median	All	0.420	0.215	.024	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RCCD1–CCRCC (DFS)

Open the CCRCC breakdown →