RCCD1

Across TCGA cell cohorts, RCCD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,354 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RCCD1-associated GO terms across cancer lineages are Telomere maintenance, Centriole assembly, and Mitotic DNA replication checkpoint signaling. Each is linked with RCCD1 in more than 10 cancer types. Because this analysis shows association rather than direction, both RCCD1-to-partner and partner-to-RCCD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere maintenance grouped by RCCD1-low versus RCCD1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RCCD1→partner) and Y-score (partner→RCCD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Telomere maintenance →	+0.063	+0.983	<.001	<.001	3	11
BLOOD_Leukemia	Centriole assembly →	+0.085	+0.970	<.001	<.001	3	11
BLOOD_Myeloma	Mitotic DNA replication checkpoint signaling →	+0.133	+0.930	.006	.004	2	11
BREAST	Resolution of DNA recombination intermediates →	+0.119	+1.304	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	DNA integrity checkpoint signaling →	+0.100	+1.338	.001	<.001	3	10
SKIN	Mitotic DNA replication →	+0.108	+0.770	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,354 associations by consensus.

Telomere maintenance by RCCD1 expression — BONE

Explore this box plot interactively →