RCCD1

Across TCGA cell cohorts, RCCD1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RCCD1-associated genes across cancer lineages are GML, CFC1, and KRTAP12-3. Each is linked with RCCD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RCCD1-to-partner and partner-to-RCCD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GML grouped by RCCD1-low versus RCCD1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RCCD1→partner) and Y-score (partner→RCCD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GML →	+0.109	+4.152	<.001	.009	3	1
BLOOD_Leukemia	CFC1 →	+0.016	+4.539	<.001	.007	3	1
BLOOD_Leukemia	KRTAP12-3 →	+0.092	+4.539	<.001	.007	3	1
BLOOD_Leukemia	FAM236A →	+0.110	+5.269	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

GML by RCCD1 expression — BLOOD_Leukemia

Explore this box plot interactively →