RCCD1-AS1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RCCD1-AS1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of RCCD1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RCCD1-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RCCD1-AS1 is over-expressed in tumor.

HNSC, COAD, and BLCA are the cancer types where RCCD1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RCCD1-AS1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
HNSCMaleIII,IV+0.307<.00112view →
COADFemaleII,III,IV+0.501<.00111view →
BLCAMaleIII,IV+0.462<.00111view →
LIHCFemaleII,III,IV+0.220<.0019view →
LUSCFemaleAll+0.443<.0016view →
LUADMaleAll+0.282<.0016view →
BRCAAllII,III,IV+0.177<.0016view →
STADMaleII,III,IV+0.367<.0014view →
CHOLMaleAll+0.878<.0013view →
KIRCFemaleII,III,IV+0.146.0053view →
ESCAAllII,III,IV+0.595.0112view →
UCECAllAll+0.240.0212view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

RCCD1-AS1–HNSC

Tumor-vs-normal expression box plot for RCCD1-AS1 RNA in HNSC.

Open the HNSC breakdown →

Exploration