Across TCGA pan-cancer cohorts, RCC2P4 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RCC2P4’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where RCC2P4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RCC2P4 is over-expressed in tumor.
COAD and STAD are the cancer types where RCC2P4 tumor–normal differential expression is most reproducible.