RCC2

Across TCGA patient cohorts, RCC2 protein abundance is significantly associated with the RNA expression of many other genes, with 15,300 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RCC2-associated genes across cancer lineages are CEP85, MYBL2, and ASF1B. Each is linked with RCC2 in more than 9 cancer types. Because this analysis shows association rather than direction, both RCC2-to-partner and partner-to-RCC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RCC2 versus CEP85 in LSCC, with a Pearson correlation of 0.77.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RCC2→partner) and Y-score (partner→RCC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CEP85 →	+0.931	+0.613	<.001	<.001	3	10
BRCA	MYBL2 →	+1.373	+0.270	<.001	<.001	3	9
UCEC	ASF1B →	+0.773	+0.262	<.001	<.001	3	9
UCEC	TIMELESS →	+0.836	+0.257	<.001	<.001	3	9
UCEC	MCM3 →	+0.924	+0.337	<.001	<.001	3	9
BRCA	AURKB →	+1.237	+0.311	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,300 associations by consensus.

RCC2 vs CEP85 — LSCC

Explore this scatter interactively →