RCC2

Across TCGA cell cohorts, RCC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,521 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RCC2-associated GO terms across cancer lineages are Regulation of DNA stability, Cell cycle phase transition, and mRNA transport. Each is linked with RCC2 in more than 14 cancer types. Because this analysis shows association rather than direction, both RCC2-to-partner and partner-to-RCC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA stability grouped by RCC2-low versus RCC2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RCC2→partner) and Y-score (partner→RCC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of DNA stability →	+0.138	+0.789	<.001	.002	3	15
BONE	Cell cycle phase transition →	+0.092	+0.894	.001	.003	3	13
BONE	mRNA transport →	+0.102	+0.893	<.001	.005	3	13
BONE	Regulation of DNA repair →	+0.076	+1.039	<.001	<.001	3	13
LIVER	Epigenetic regulation of gene expression →	+0.071	+1.134	.001	<.001	3	12
BONE	Regulation of G2/MI transition of meiotic cell cycle →	+0.146	+0.984	.008	.006	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,521 associations by consensus.

Regulation of DNA stability by RCC2 expression — BONE

Explore this box plot interactively →