RCC2

Across TCGA cell cohorts, RCC2 mutation is significantly associated with the mutation status of many other genes, with 1,700 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RCC2-associated genes across cancer lineages are ZNF710, ADAR, and UGT2A1. Each is linked with RCC2 in more than 3 cancer types. Because this analysis shows association rather than direction, both RCC2-to-partner and partner-to-RCC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF710 grouped by RCC2-low versus RCC2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RCC2→partner) and Y-score (partner→RCC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ZNF710 →	+4.584	+4.584	.007	.007	1	4
BLOOD_Leukemia	ADAR →	+3.823	+4.430	.001	.001	1	3
BLOOD_Leukemia	UGT2A1 →	+4.560	+4.309	.007	.007	1	3
BLOOD_Leukemia	SLC38A9 →	+6.145	+5.479	<.001	<.001	1	3
BLOOD_Lymphoma	ZNF700 →	+5.584	+5.014	.003	.003	1	3
LARGE_INTESTINE	ZNF839 →	+2.321	+2.919	.003	.003	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,700 associations by consensus.

ZNF710 by RCC2 expression — BLOOD_Lymphoma

Explore this box plot interactively →