RCBTB2

Across TCGA patient cohorts, RCBTB2 mutation is significantly associated with the RNA expression of many other genes, with 1,512 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RCBTB2-associated genes across cancer lineages are LINC00587, RNU6-921P, and MIR99B. Each is linked with RCBTB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RCBTB2-to-partner and partner-to-RCBTB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00587 grouped by RCBTB2-low versus RCBTB2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RCBTB2→partner) and Y-score (partner→RCBTB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC00587 →	+0.295	+3.894	.001	.004	3	2
SKCM	RNU6-921P →	+0.254	+3.669	<.001	.006	3	2
SKCM	MIR99B →	+0.408	+3.408	<.001	.009	3	2
SKCM	HNF4GP1 →	+0.055	+4.362	<.001	.001	3	2
BLCA	HMGB1P30 →	+0.110	+6.018	<.001	.002	3	2
BLCA	RNU6-255P →	+0.354	+5.588	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,512 associations by consensus.

LINC00587 by RCBTB2 expression — SKCM

Explore this box plot interactively →