RCBTB2

Across TCGA cell cohorts, RCBTB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,956 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RCBTB2-associated GO terms across cancer lineages are Regulation of cilium assembly, Protein polymerization, and Establishment of spindle orientation. Each is linked with RCBTB2 in more than 8 cancer types. Because this analysis shows association rather than direction, both RCBTB2-to-partner and partner-to-RCBTB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cilium assembly grouped by RCBTB2-low versus RCBTB2-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RCBTB2→partner) and Y-score (partner→RCBTB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of cilium assembly →	+0.052	+0.645	<.001	<.001	3	9
LUNG_NSCLC_LUSC	Protein polymerization →	+0.090	+0.919	.001	.001	3	9
LUNG_SCLC	Establishment of spindle orientation →	+0.090	+0.971	.001	.002	3	9
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cell cycle G1/S phase transition →	+0.067	+0.652	.001	.006	3	8
BONE	UTP biosynthetic process →	-0.113	-0.888	.003	.001	3	8
OESOPHAGUS	Negative regulation of cell cycle process →	+0.096	+1.184	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,956 associations by consensus.

Regulation of cilium assembly by RCBTB2 expression — LARGE_INTESTINE

Explore this box plot interactively →