RCBTB2

Across TCGA cell cohorts, RCBTB2 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RCBTB2-associated genes across cancer lineages are GHRHR, TCF21, and TACR3. Each is linked with RCBTB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RCBTB2-to-partner and partner-to-RCBTB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GHRHR grouped by RCBTB2-low versus RCBTB2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RCBTB2→partner) and Y-score (partner→RCBTB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GHRHR →	+0.451	+4.705	<.001	.003	3	1
BLOOD_Leukemia	TCF21 →	+0.011	+4.705	<.001	.003	3	1
BLOOD_Leukemia	TACR3 →	+0.038	+5.060	<.001	.001	3	1
BLOOD_Leukemia	OR10T2 →	+0.707	+4.276	<.001	.007	3	1
BLOOD_Leukemia	OR10R2 →	+1.349	+4.551	.004	.004	3	1
OVARY	ASB17 →	+0.014	+4.222	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

GHRHR by RCBTB2 expression — BLOOD_Leukemia

Explore this box plot interactively →