RCBTB1

Across TCGA patient cohorts, RCBTB1 mutation is significantly associated with the RNA expression of many other genes, with 3,277 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RCBTB1-associated genes across cancer lineages are MED15P4, PSAT1P4, and RNU6-1273P. Each is linked with RCBTB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RCBTB1-to-partner and partner-to-RCBTB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MED15P4 grouped by RCBTB1-low versus RCBTB1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RCBTB1→partner) and Y-score (partner→RCBTB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MED15P4 →	+0.605	+5.044	<.001	.009	3	2
UCEC	PSAT1P4 →	+0.120	+1.978	.001	<.001	3	2
BLCA	RNU6-1273P →	+0.373	+7.640	<.001	.009	3	2
SKCM	RN7SL627P →	+0.111	+5.080	<.001	.004	3	2
SKCM	OR2M4 →	+0.241	+4.215	<.001	.009	3	2
SKCM	RNA5SP393 →	+0.574	+5.075	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,277 associations by consensus.

MED15P4 by RCBTB1 expression — LUAD

Explore this box plot interactively →