RCBTB1

Across TCGA cell cohorts, RCBTB1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RCBTB1-associated genes across cancer lineages are C18orf63 and ZCCHC13. Each is linked with RCBTB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RCBTB1-to-partner and partner-to-RCBTB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C18orf63 grouped by RCBTB1-low versus RCBTB1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RCBTB1→partner) and Y-score (partner→RCBTB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	C18orf63 →	+0.019	+4.867	<.001	.009	3	1
LUNG_NSCLC_LUAD	ZCCHC13 →	+0.023	+6.266	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

C18orf63 by RCBTB1 expression — BLOOD_Lymphoma

Explore this box plot interactively →