RCAN1

Across TCGA cell cohorts, RCAN1 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RCAN1-associated genes across cancer lineages are SCGB1C1, SMIM9, and CD300LD. Each is linked with RCAN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RCAN1-to-partner and partner-to-RCAN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCGB1C1 grouped by RCAN1-low versus RCAN1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RCAN1→partner) and Y-score (partner→RCAN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	SCGB1C1 →	+0.336	+4.981	<.001	.008	3	1
CNS	SMIM9 →	+0.032	+5.754	<.001	.002	3	1
CNS	CD300LD →	+0.042	+5.754	<.001	.002	3	1
CNS	OR2B3 →	+0.025	+5.321	<.001	.005	3	1
CNS	TARM1 →	+0.032	+5.321	<.001	.005	3	1
CNS	GUCA2B →	+0.057	+4.981	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

SCGB1C1 by RCAN1 expression — CNS

Explore this box plot interactively →