RC3H1

Across TCGA pan-cancer cohorts, RC3H1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated RC3H1 data layer compared with 26 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RC3H1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated RC3H1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and PDAC show a favorable association.

UCEC, PDAC, and LUAD are the cancer types where RC3H1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	1.000	0.905	.008	32	view →
PDAC	OS	Median	All	0.945	0.768	<.001	21	view →
LUAD	DFS	Median	All	0.667	0.948	.010	6	view →
CCRCC	OS	Quartile	III,IV	0.441	0.812	.033	1	view →
HNSC	OS	Tertile	All	1.000	0.958	.046	1	view →
GBM	DFS	Median	All	0.638	0.779	.028	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

RC3H1–UCEC (OS)

Open the UCEC breakdown →