RBPMSLP

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RBPMSLP RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated RBPMSLP data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RBPMSLP RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RBPMSLP expression acts as an unfavorable survival marker, although some lineages such as HNSC and BLCA show a favorable association.

ACC, UVM, and TGCT are the cancer types where RBPMSLP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ACCDFSTertileII,III,IV0.1890.665<.00196view →
UVMOSTertileIII,IV0.0370.809<.00154view →
TGCTDFSQuartileII,III,IV0.5860.996.00230view →
THYMDFSQuartileII,III,IV0.6460.946.00426view →
DLBCDFSMedianIV0.1281.000.01719view →
HNSCDFSQuartileAll0.4810.280.00419view →
READOSTertileII,III,IV0.6220.945.00918view →
BLCADFSTertileIII,IV0.5190.283.01914view →
SKCMOSQuartileII,III,IV0.2130.351.0279view →
BRCADFSTertileIII,IV0.3610.560.0228view →
STADDFSTertileIV0.1300.551.0076view →
LAMLDFSMedianAll0.2640.511.0266view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

RBPMSLP–ACC (DFS)

Kaplan–Meier survival curve for RBPMSLP RNA-high vs -low samples in ACC.

Open the ACC breakdown →

Exploration