RBPMS2

Across TCGA patient cohorts, RBPMS2 mutation is significantly associated with the RNA expression of many other genes, with 3,632 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBPMS2-associated genes across cancer lineages are AARSD1, MIR3922, and FAM219B. Each is linked with RBPMS2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBPMS2-to-partner and partner-to-RBPMS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AARSD1 grouped by RBPMS2-low versus RBPMS2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBPMS2→partner) and Y-score (partner→RBPMS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AARSD1 →	+0.376	+2.732	.002	.003	3	2
LUAD	MIR3922 →	+0.547	+5.279	.004	.006	3	2
UCEC	FAM219B →	+0.590	+3.906	<.001	<.001	3	2
UCEC	PFAS →	+0.637	+2.523	<.001	.001	3	2
UCEC	MTUS2-AS1 →	+0.232	+2.053	<.001	.005	3	2
UCEC	ELMOD2 →	+0.556	+3.202	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,632 associations by consensus.

AARSD1 by RBPMS2 expression — UCEC

Explore this box plot interactively →