RBPMS2

Across TCGA patient cohorts, RBPMS2 mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBPMS2-associated genes across cancer lineages are eIF4G, ACC1, and ACVRL1. Each is linked with RBPMS2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBPMS2-to-partner and partner-to-RBPMS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4G grouped by RBPMS2-low versus RBPMS2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBPMS2→partner) and Y-score (partner→RBPMS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4G →	+0.274	+1.700	.037	.044	3	1
UCEC	ACC1 →	+0.324	+3.013	.036	.018	3	1
UCEC	ACVRL1 →	-0.115	-1.700	.047	.044	3	1
UCEC	Notch1 →	+0.191	+3.183	.001	.009	3	1
UCEC	p62 Lck ligand →	+0.469	+3.331	<.001	.005	3	1
UCEC	PRAS40_pT246 →	+0.172	+3.000	.018	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

eIF4G by RBPMS2 expression — UCEC

Explore this box plot interactively →