RBPMS

Across TCGA pan-cancer cohorts, RBPMS RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of RBPMS’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where RBPMS RNA is repressed in tumor relative to normal tissue. In most cancer types RBPMS is over-expressed in tumor, although a few such as BLCA and KICH show the opposite, repressed pattern.

BLCA, KICH, and KIRP are the cancer types where RBPMS tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RBPMS RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	III,IV	−2.932	<.001	10	view →
KICH	Male	II,III,IV	−1.341	<.001	10	view →
KIRP	All	II,III,IV	+0.743	<.001	9	view →
LUAD	Male	All	−1.006	<.001	8	view →
BRCA	Female	All	−1.002	<.001	8	view →
LUSC	Male	All	−1.791	<.001	7	view →
UCEC	All	All	−2.250	<.001	6	view →
KIRC	All	All	+0.315	<.001	5	view →
HNSC	All	All	−0.477	.014	4	view →
CHOL	All	All	+2.255	<.001	3	view →
THCA	All	II,III,IV	−0.250	.009	3	view →
STAD	Female	All	−1.160	.042	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

RBPMS–BLCA

Open the BLCA breakdown →