Across TCGA pan-cancer cohorts, RBPJP6 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RBPJP6 data layer.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RBPJP6 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RBPJP6 expression acts as an unfavorable survival marker, although some lineages such as ESCA and LUAD show a favorable association.
KIRC, LIHC, and KICH are the cancer types where RBPJP6 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.