RBP7

Across TCGA pan-cancer cohorts, RBP7 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated RBP7 data layer compared with 28 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RBP7 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RBP7 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

HNSC, PDAC, and LUAD are the cancer types where RBP7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	II,III,IV	0.849	0.698	.006	31	view →
PDAC	DFS	Quartile	II,III,IV	0.183	0.515	.001	27	view →
LUAD	OS	Median	III,IV	0.750	0.997	.031	3	view →
GBM	OS	Median	All	0.309	0.433	.047	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

RBP7–HNSC (DFS)

Open the HNSC breakdown →