RBP7

Across TCGA patient cohorts, RBP7 mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. COAD shows the largest number of these associations.

The most reproducible RBP7-associated genes across cancer lineages are MTND5P33, GPX6, and ATF1P1. Each is linked with RBP7 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBP7-to-partner and partner-to-RBP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND5P33 grouped by RBP7-low versus RBP7-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBP7→partner) and Y-score (partner→RBP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MTND5P33 →	+0.238	+6.122	<.001	.002	3	2
COAD	GPX6 →	+0.175	+5.435	<.001	.005	3	1
COAD	ATF1P1 →	+0.228	+6.392	.003	.001	3	1
COAD	PACRG-AS2 →	+0.192	+6.721	<.001	<.001	3	1
COAD	MTND4P1 →	+0.194	+5.790	<.001	.003	3	1
COAD	PIGPP3 →	+0.248	+5.017	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

MTND5P33 by RBP7 expression — COAD

Explore this box plot interactively →