RBP7

Across TCGA cell cohorts, RBP7 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,540 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible RBP7-associated GO terms across cancer lineages are RNA splicing, via transesterification reactions with bulged adenosine as nucleophile, mRNA splicing, via spliceosome, and RNA splicing, via transesterification reactions. Each is linked with RBP7 in more than 9 cancer types. Because this analysis shows association rather than direction, both RBP7-to-partner and partner-to-RBP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA splicing, via transesterification reactions with bulged adenosine as nucleophile grouped by RBP7-low versus RBP7-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RBP7→partner) and Y-score (partner→RBP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.082	+3.244	.003	<.001	3	10
OESOPHAGUS	mRNA splicing, via spliceosome →	+0.082	+3.244	.003	<.001	3	10
OESOPHAGUS	RNA splicing, via transesterification reactions →	+0.082	+3.244	.003	<.001	3	10
BREAST	Protein K11-linked ubiquitination →	+0.077	+2.477	.001	.002	3	9
LUNG_NSCLC_LUAD	Protein-RNA complex assembly →	+0.034	+1.414	<.001	<.001	3	9
OESOPHAGUS	Mitotic cell cycle phase transition →	+0.051	+1.860	<.001	.004	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,540 associations by consensus.

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile by RBP7 expression — OESOPHAGUS

Explore this box plot interactively →