RBMXL3

Across TCGA patient cohorts, RBMXL3 mutation is significantly associated with the RNA expression of many other genes, with 3,612 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBMXL3-associated genes across cancer lineages are TAF9, RNA5SP367, and NPBWR2. Each is linked with RBMXL3 in more than 2 cancer types. Because this analysis shows association rather than direction, both RBMXL3-to-partner and partner-to-RBMXL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAF9 grouped by RBMXL3-low versus RBMXL3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBMXL3→partner) and Y-score (partner→RBMXL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TAF9 →	+0.407	+2.343	<.001	<.001	3	3
LIHC	RNA5SP367 →	+0.121	+4.157	<.001	.008	3	3
SCLC	NPBWR2 →	+0.129	+4.299	<.001	.002	3	2
UCEC	ZNHIT3 →	+0.333	+1.775	<.001	<.001	3	2
UCEC	TUBGCP5 →	+0.346	+1.748	<.001	<.001	3	2
COAD	SRCIN1 →	-0.666	-3.767	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,612 associations by consensus.

TAF9 by RBMXL3 expression — UCEC

Explore this box plot interactively →