RBMXL3

Across TCGA cell cohorts, RBMXL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 143 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible RBMXL3-associated GO terms across cancer lineages are Cochlea development, Mitophagy, and Synaptic vesicle fusion to presynaptic active zone membrane. Each is linked with RBMXL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBMXL3-to-partner and partner-to-RBMXL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cochlea development grouped by RBMXL3-low versus RBMXL3-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RBMXL3→partner) and Y-score (partner→RBMXL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Cochlea development →	-0.092	-0.006	.003	.008	3	2
LUNG_SCLC	Mitophagy →	+0.058	+0.006	.004	.008	3	2
CNS	Synaptic vesicle fusion to presynaptic active zone membrane →	-0.116	-0.007	<.001	<.001	3	2
CNS	Vesicle fusion to plasma membrane →	-0.116	-0.007	<.001	<.001	3	2
LUNG_NSCLC_LUAD	Negative regulation of RNA polymerase II transcription preinitiation complex assembly →	+0.089	+0.003	.006	.006	3	2
LUNG_NSCLC_LUAD	Lipoprotein biosynthetic process →	+0.083	+0.002	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 143 associations by consensus.

Cochlea development by RBMXL3 expression — LUNG_SCLC

Explore this box plot interactively →