RBMXL3

Across TCGA cell cohorts, RBMXL3 mutation is significantly associated with the RNA expression of many other genes, with 606 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RBMXL3-associated genes across cancer lineages are MAGEB5, FAM200B, and TXLNA. Each is linked with RBMXL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBMXL3-to-partner and partner-to-RBMXL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB5 grouped by RBMXL3-low versus RBMXL3-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBMXL3→partner) and Y-score (partner→RBMXL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	MAGEB5 →	+0.033	+4.643	<.001	.008	3	2
LARGE_INTESTINE	FAM200B →	+0.674	+2.850	<.001	<.001	3	2
LARGE_INTESTINE	TXLNA →	+0.615	+3.252	.001	.002	3	2
SKIN	HPGDS →	+0.043	+2.560	.001	.009	3	1
SKIN	CYP26B1 →	+1.384	+3.064	<.001	.009	3	1
LARGE_INTESTINE	HSCB →	+0.483	+3.321	.004	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 606 associations by consensus.

MAGEB5 by RBMXL3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →