RBMXL2

Across TCGA patient cohorts, RBMXL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,024 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RBMXL2-associated GO terms across cancer lineages are Positive regulation of DNA repair, Positive regulation of double-strand break repair, and Methylation. Each is linked with RBMXL2 in more than 23 cancer types. Because this analysis shows association rather than direction, both RBMXL2-to-partner and partner-to-RBMXL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by RBMXL2-low versus RBMXL2-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RBMXL2→partner) and Y-score (partner→RBMXL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Positive regulation of DNA repair →	+0.082	+0.518	<.001	<.001	3	24
SCLC	Positive regulation of double-strand break repair →	+0.058	+0.365	<.001	<.001	3	20
STAD	Methylation →	+0.030	+0.057	<.001	<.001	3	20
STAD	Protein export from nucleus →	+0.032	+0.049	<.001	<.001	3	20
STAD	Positive regulation of DNA metabolic process →	+0.037	+0.057	<.001	<.001	3	19
STAD	Mitochondrial gene expression →	+0.036	+0.051	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,024 associations by consensus.

Positive regulation of DNA repair by RBMXL2 expression — SCLC

Explore this box plot interactively →