RBMXL1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RBMXL1 mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBMXL1-associated genes across cancer lineages are A-Raf_pS299, JNK2, and P-Cadherin. Each is linked with RBMXL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBMXL1-to-partner and partner-to-RBMXL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBMXL1→partner) and Y-score (partner→RBMXL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECA-Raf_pS299 →-0.101-1.906.016.01532
UCECJNK2 →+0.190+2.000.006.00332
UCECP-Cadherin →-0.121-3.169.017.01832
UCECPDCD4 →-0.552-2.115<.001.01632
UCECRictor_pT1135 →-0.088-2.584.015.01032
UCECTIGAR →+0.109+1.689.043.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

Exploration