RBMX

Across TCGA patient cohorts, RBMX mutation is significantly associated with the total protein of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBMX-associated genes across cancer lineages are Caspase-7-cleavedD198, eEF2, and EGFR_pY1068. Each is linked with RBMX in more than 1 cancer types. Because this analysis shows association rather than direction, both RBMX-to-partner and partner-to-RBMX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by RBMX-low versus RBMX-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBMX→partner) and Y-score (partner→RBMX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.642	+2.019	<.001	.005	3	2
UCEC	eEF2 →	+0.310	+3.584	.008	.002	3	1
UCEC	EGFR_pY1068 →	-0.247	-1.392	.002	.019	3	1
UCEC	A-Raf_pS299 →	-0.129	-2.584	.001	.001	3	1
UCEC	ERK2 →	+0.173	+1.652	.006	.006	3	1
UCEC	GATA6 →	-0.122	-1.433	.023	.023	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

Caspase-7-cleavedD198 by RBMX expression — UCEC

Explore this box plot interactively →