RBMX

Across TCGA cell cohorts, RBMX RNA expression is significantly associated with the go_rna of many other GO terms, with 5,854 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RBMX-associated GO terms across cancer lineages are DNA replication initiation, Sister chromatid cohesion, and Mitotic spindle assembly. Each is linked with RBMX in more than 17 cancer types. Because this analysis shows association rather than direction, both RBMX-to-partner and partner-to-RBMX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by RBMX-low versus RBMX-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RBMX→partner) and Y-score (partner→RBMX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA replication initiation →	+0.149	+0.877	.008	.001	3	18
UPPER_AERODIGESTIVE_TRACT	Sister chromatid cohesion →	+0.115	+1.240	<.001	<.001	3	17
OVARY	Mitotic spindle assembly →	+0.098	+0.794	<.001	<.001	3	17
URINARY_TRACT	Positive regulation of chromosome condensation →	+0.258	+0.826	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	DNA strand elongation →	+0.204	+1.213	<.001	<.001	3	17
LARGE_INTESTINE	Regulation of DNA-templated DNA replication initiation →	+0.122	+0.586	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,854 associations by consensus.

DNA replication initiation by RBMX expression — BONE

Explore this box plot interactively →