RBMS3

Across TCGA cell cohorts, RBMS3 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RBMS3-associated genes across cancer lineages are KLHL40, CST9, and MRGPRG. Each is linked with RBMS3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBMS3-to-partner and partner-to-RBMS3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KLHL40 grouped by RBMS3-low versus RBMS3-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBMS3→partner) and Y-score (partner→RBMS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	KLHL40 →	+0.013	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	CST9 →	+0.119	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	MRGPRG →	+0.056	+5.209	<.001	.005	3	1
LARGE_INTESTINE	AVP →	+0.056	+3.632	<.001	.003	3	1
LARGE_INTESTINE	REG1B →	+3.348	+3.196	<.001	.007	3	1
BLOOD_Leukemia	NPFFR1 →	+0.017	+4.359	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

KLHL40 by RBMS3 expression — BLOOD_Lymphoma

Explore this box plot interactively →