RBMS3-AS2

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RBMS3-AS2 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RBMS3-AS2 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RBMS3-AS2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RBMS3-AS2 expression acts as an unfavorable survival marker, although some lineages such as UCS and ESCA show a favorable association.

KIRC, KICH, and MESO are the cancer types where RBMS3-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCOSMedianAll0.5340.709<.00186view →
KICHDFSTertileAll0.5120.962<.00176view →
MESOOSTertileAll0.3730.648<.00175view →
BLCAOSTertileIV0.1370.325.01038view →
THCAOSTertileAll0.9531.000.00534view →
UCECOSTertileIV0.2020.545.00728view →
ACCOSTertileII,III,IV0.2710.659.00626view →
LAMLDFSTertileAll0.4350.793.00124view →
CESCDFSQuartileIII,IV0.5060.859.00622view →
UCSDFSQuartileIII,IV0.7190.262.00918view →
LGGOSMedianAll0.7490.841.00416view →
UVMOSTertileIII,IV0.2040.707.02315view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

Exploration