RBMS3-AS1

Across TCGA pan-cancer cohorts, RBMS3-AS1 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RBMS3-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RBMS3-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RBMS3-AS1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and THYM show a favorable association.

KIRC, THCA, and DLBC are the cancer types where RBMS3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Quartile	II,III,IV	0.667	0.826	.002	106	view →
THCA	OS	Median	All	0.976	0.999	<.001	82	view →
DLBC	DFS	Tertile	II,III,IV	0.314	0.881	<.001	54	view →
READ	DFS	Tertile	II,III,IV	0.224	0.676	.003	54	view →
ACC	DFS	Tertile	IV	0.010	0.383	<.001	27	view →
KICH	DFS	Tertile	III,IV	0.065	0.835	.020	24	view →
MESO	OS	Tertile	II,III,IV	0.287	0.425	.027	21	view →
SKCM	OS	Tertile	IV	0.179	0.755	<.001	18	view →
UCEC	DFS	Tertile	IV	0.212	0.602	.014	18	view →
ESCA	DFS	Tertile	III,IV	0.481	0.252	.014	15	view →
LUAD	DFS	Tertile	II,III,IV	0.282	0.543	.032	15	view →
BLCA	DFS	Tertile	All	0.412	0.633	.034	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

RBMS3-AS1–KIRC (DFS)

Open the KIRC breakdown →