RBMS2

Across TCGA patient cohorts, RBMS2 mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBMS2-associated genes across cancer lineages are Acetyl-a-Tubulin-Lys40, Cyclin-E2, and EGFR_pY1068. Each is linked with RBMS2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBMS2-to-partner and partner-to-RBMS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Acetyl-a-Tubulin-Lys40 grouped by RBMS2-low versus RBMS2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBMS2→partner) and Y-score (partner→RBMS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.553	+3.087	.006	<.001	3	2
UCEC	Cyclin-E2 →	+0.166	+1.594	.014	.042	3	2
UCEC	EGFR_pY1068 →	-0.298	-1.906	.003	.016	3	1
UCEC	eIF4E →	+0.175	+2.415	.039	.003	3	1
UCEC	GAPDH →	+0.573	+3.321	.007	.009	3	1
UCEC	JNK2 →	+0.230	+2.331	.004	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

Acetyl-a-Tubulin-Lys40 by RBMS2 expression — UCEC

Explore this box plot interactively →