RBMS1

Across TCGA patient cohorts, RBMS1 mutation is significantly associated with the RNA expression of many other genes, with 1,887 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBMS1-associated genes across cancer lineages are OR6C4, RN7SKP27, and LINC01943. Each is linked with RBMS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBMS1-to-partner and partner-to-RBMS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6C4 grouped by RBMS1-low versus RBMS1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBMS1→partner) and Y-score (partner→RBMS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	OR6C4 →	+0.031	+4.136	<.001	.008	3	2
SKCM	RN7SKP27 →	+0.095	+5.810	<.001	<.001	3	2
UCEC	LINC01943 →	+0.513	+2.839	<.001	.001	3	2
UCEC	SKA1 →	+0.649	+3.828	<.001	<.001	3	2
UCEC	SNRNP25 →	+0.379	+2.212	.003	<.001	3	2
UCEC	TEDC2 →	+0.543	+2.158	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,887 associations by consensus.

OR6C4 by RBMS1 expression — COAD

Explore this box plot interactively →