RBM8A

Across TCGA cell cohorts, RBM8A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,821 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RBM8A-associated GO terms across cancer lineages are Spliceosome conformational change to release U4 (or U4atac) and U1 (or U11), Positive regulation of cell cycle phase transition, and DNA-templated DNA replication. Each is linked with RBM8A in more than 15 cancer types. Because this analysis shows association rather than direction, both RBM8A-to-partner and partner-to-RBM8A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) grouped by RBM8A-low versus RBM8A-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM8A→partner) and Y-score (partner→RBM8A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) →	+0.093	+0.692	.006	.004	3	16
LUNG_NSCLC_LUSC	Positive regulation of cell cycle phase transition →	+0.082	+0.605	.003	.004	3	15
SOFT_TISSUE	DNA-templated DNA replication →	+0.113	+0.834	<.001	<.001	3	15
BLOOD_Lymphoma	Regulation of double-strand break repair via homologous recombination →	+0.077	+0.881	<.001	<.001	3	14
SOFT_TISSUE	Chromosome condensation →	+0.146	+0.752	<.001	<.001	3	14
SOFT_TISSUE	Positive regulation of mitotic cell cycle →	+0.087	+0.863	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,821 associations by consensus.

Spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) by RBM8A expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →