RBM8A

Across TCGA cell cohorts, RBM8A protein abundance is significantly associated with the go_rna of many other GO terms, with 3,358 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RBM8A-associated GO terms across cancer lineages are Metanephric proximal tubule development, Ganglioside catabolic process, and Regulation of amyloid fibril formation. Each is linked with RBM8A in more than 7 cancer types. Because this analysis shows association rather than direction, both RBM8A-to-partner and partner-to-RBM8A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Metanephric proximal tubule development grouped by RBM8A-low versus RBM8A-high in OVARY.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM8A→partner) and Y-score (partner→RBM8A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Metanephric proximal tubule development →	-0.248	-0.778	.007	.001	2	8
BLOOD_Lymphoma	Ganglioside catabolic process →	+0.162	+0.981	<.001	.002	3	6
OVARY	Regulation of amyloid fibril formation →	+0.158	+0.784	<.001	.001	3	6
LIVER	Interleukin-12-mediated signaling pathway →	+0.213	+0.887	.001	.005	3	6
OVARY	Negative regulation of receptor guanylyl cyclase signaling pathway →	+1.136	+0.851	.006	.001	2	6
BLOOD_Lymphoma	Glycosphingolipid catabolic process →	+0.142	+0.700	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,358 associations by consensus.

Metanephric proximal tubule development by RBM8A expression — OVARY

Explore this box plot interactively →