RBM7

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RBM7 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated RBM7 data layer compared with 26 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher RBM7 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated RBM7 expression acts as an unfavorable survival marker.

OV and LIHC are the cancer types where RBM7 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
OVDFSMedianAll0.2790.541.04018view →
LIHCOSMedianAll0.1880.669.0416view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

RBM7–OV (DFS)

Kaplan–Meier survival curve for RBM7 mutant vs wild-type samples in OV.

Open the OV breakdown →

Exploration