RBM5

Across TCGA patient cohorts, RBM5 mutation is significantly associated with the RNA expression of many other genes, with 3,577 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM5-associated genes across cancer lineages are MIR182, ANP32BP1, and RNU6-249P. Each is linked with RBM5 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM5-to-partner and partner-to-RBM5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR182 grouped by RBM5-low versus RBM5-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM5→partner) and Y-score (partner→RBM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR182 →	+0.449	+5.020	<.001	.009	3	2
UCEC	ANP32BP1 →	+0.213	+1.676	.002	.001	3	2
BLCA	RNU6-249P →	+0.315	+3.691	.006	.001	3	2
BLCA	MIR191 →	+0.311	+3.193	.001	.006	3	2
BLCA	RNU6-747P →	+0.231	+6.636	<.001	<.001	3	2
CESC	RNA5SP175 →	+0.411	+2.590	.007	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,577 associations by consensus.

MIR182 by RBM5 expression — BRCA

Explore this box plot interactively →