RBM5

Across TCGA cell cohorts, RBM5 mutation is significantly associated with the drug of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RBM5-associated genes across cancer lineages are PRT062607, 123829, and Savolitinib. Each is linked with RBM5 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM5-to-partner and partner-to-RBM5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRT062607 grouped by RBM5-low versus RBM5-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM5→partner) and Y-score (partner→RBM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PRT062607 →	+0.640	+2.769	.010	.040	3	1
LARGE_INTESTINE	123829 →	+0.646	+2.649	.026	.046	3	1
LARGE_INTESTINE	Savolitinib →	+0.361	+2.777	.044	.038	3	1
LARGE_INTESTINE	GSK2110183B →	+0.603	+2.649	.048	.046	2	1
LARGE_INTESTINE	Teniposide →	+0.529	+2.649	.048	.046	2	1
LARGE_INTESTINE	P22077 →	+0.662	+2.649	.003	.046	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

PRT062607 by RBM5 expression — LARGE_INTESTINE

Explore this box plot interactively →