RBM4B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RBM4B mutation is significantly associated with the RNA expression of many other genes, with 434 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM4B-associated genes across cancer lineages are RN7SL98P, MIR6803, and RNA5SP412. Each is linked with RBM4B in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM4B-to-partner and partner-to-RBM4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL98P grouped by RBM4B-low versus RBM4B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM4B→partner) and Y-score (partner→RBM4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRN7SL98P →+0.149+2.523<.001.00132
UCECMIR6803 →+0.130+4.230<.001.00432
BLCARNA5SP412 →+0.343+7.640<.001.00932
BLCAMIR501 →+0.462+7.640<.001.00931
LUADLINC01957 →+0.074+7.930<.001.00831
LUADRNA5SP54 →+0.467+7.930<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 434 associations by consensus.

RN7SL98P by RBM4B expression — UCEC

Box plot of RN7SL98P in RBM4B-low vs RBM4B-high samples in UCEC.

Explore this box plot interactively →

Exploration