RBM48

Across TCGA patient cohorts, RBM48 mutation is significantly associated with the RNA expression of many other genes, with 296 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM48-associated genes across cancer lineages are LINC00428, MIR588, and RAB5CP1. Each is linked with RBM48 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM48-to-partner and partner-to-RBM48 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00428 grouped by RBM48-low versus RBM48-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM48→partner) and Y-score (partner→RBM48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC00428 →	+0.225	+5.306	<.001	.006	3	2
LUAD	MIR588 →	+0.680	+5.631	<.001	.004	3	2
SKCM	RAB5CP1 →	+0.152	+3.945	<.001	.003	3	2
CESC	SLC25A15P2 →	+0.165	+5.306	<.001	.006	3	2
CESC	MIR4662B →	+0.529	+5.539	<.001	.004	3	2
UCEC	EIF3JP1 →	+0.285	+2.690	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 296 associations by consensus.

LINC00428 by RBM48 expression — CESC

Explore this box plot interactively →