RBM48

Across TCGA cell cohorts, RBM48 mutation is significantly associated with the drug of many other genes, with 25 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RBM48-associated genes across cancer lineages are 5-Fluorouracil, Niraparib, and LMP744. Each is linked with RBM48 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM48-to-partner and partner-to-RBM48 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 5-Fluorouracil grouped by RBM48-low versus RBM48-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM48→partner) and Y-score (partner→RBM48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	5-Fluorouracil →	+0.621	+2.991	.023	.018	3	1
LARGE_INTESTINE	Niraparib →	+0.392	+2.868	.019	.022	3	1
LARGE_INTESTINE	LMP744 →	+0.803	+2.649	.017	.046	3	1
LARGE_INTESTINE	I-BRD9 →	+0.415	+2.649	.034	.046	3	1
LARGE_INTESTINE	ETP-45835 →	+0.246	+2.652	.042	.045	3	1
LARGE_INTESTINE	CCT007093 →	+0.302	+2.649	.043	.046	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

5-Fluorouracil by RBM48 expression — LARGE_INTESTINE

Explore this box plot interactively →