RBM46

Across TCGA cell cohorts, RBM46 mutation is significantly associated with the RNA expression of many other genes, with 45 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RBM46-associated genes across cancer lineages are MS4A13, ASPN, and SH3GL2. Each is linked with RBM46 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM46-to-partner and partner-to-RBM46 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MS4A13 grouped by RBM46-low versus RBM46-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM46→partner) and Y-score (partner→RBM46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	MS4A13 →	+0.290	+3.714	<.001	.006	3	2
LARGE_INTESTINE	ASPN →	+0.034	+3.648	.006	.002	3	1
LARGE_INTESTINE	SH3GL2 →	+1.136	+3.474	.004	.003	3	1
LARGE_INTESTINE	ZNF831 →	+0.010	+2.688	<.001	.008	3	1
LARGE_INTESTINE	CLPSL2 →	+0.649	+3.304	<.001	.008	3	1
LUNG_NSCLC_LUAD	CSH1 →	+0.048	+3.343	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

MS4A13 by RBM46 expression — BLOOD_Lymphoma

Explore this box plot interactively →