RBM45

Across TCGA patient cohorts, RBM45 mutation is significantly associated with the RNA expression of many other genes, with 1,854 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM45-associated genes across cancer lineages are SMSP1, MBIP, and ZIC3. Each is linked with RBM45 in more than 2 cancer types. Because this analysis shows association rather than direction, both RBM45-to-partner and partner-to-RBM45 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SMSP1 grouped by RBM45-low versus RBM45-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM45→partner) and Y-score (partner→RBM45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	SMSP1 →	+0.102	+5.103	<.001	.008	3	3
UCEC	MBIP →	+0.599	+2.673	.003	<.001	3	3
LUSC	ZIC3 →	+1.308	+3.683	<.001	.004	3	2
LUSC	MIR1302-5 →	+0.291	+3.371	<.001	.002	3	2
LUSC	MTND4LP17 →	+0.072	+4.517	<.001	.004	3	2
COAD	LINC02403 →	+0.204	+4.308	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,854 associations by consensus.

SMSP1 by RBM45 expression — CESC

Explore this box plot interactively →