Across TCGA cell cohorts, RBM43 mutation is significantly associated with the mutation status of many other genes, with 2,364 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RBM43-associated genes across cancer lineages are NBR1, ACP4, and HSPB8. Each is linked with RBM43 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM43-to-partner and partner-to-RBM43 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM43→partner) and Y-score (partner→RBM43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	NBR1 →	+4.502	+5.066	.007	.007	1	2
SKIN	ACP4 →	+4.824	+5.392	.004	.004	1	2
SKIN	HSPB8 →	+5.824	+5.824	.002	.002	1	2
SKIN	RTKN2 →	+4.239	+5.053	.007	.007	1	2
LARGE_INTESTINE	TRAF3IP2 →	+3.584	+3.007	.008	.008	1	2
LARGE_INTESTINE	OTUD5 →	+2.678	+2.807	.006	.006	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,364 associations by consensus.

Exploration

RBM43 survival (RNA) · tumor vs normal (RNA) · all RBM43 data types